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Motif ID: SOX{8,9,10}.p2

Z-value: 1.605

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_183970093	1.805	NM_031935	HMCN1	hemicentin 1
chr6_+_105511615	1.541	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr19_-_60369731	1.241	NM_178837	C19orf51	chromosome 19 open reading frame 51
chr13_+_112704077	1.174		MCF2L	MCF.2 cell line derived transforming sequence-like
chr1_+_200449905	1.054	NM_001017404	LGR6	leucine-rich repeat containing G protein-coupled receptor 6
chr5_-_39461054	1.008	NM_001343	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_-_27171600	1.007		HOXA9	homeobox A9
chr4_-_7991992	1.000	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr11_+_63710206	0.995		STIP1	stress-induced-phosphoprotein 1
chr11_+_63710242	0.970		STIP1	stress-induced-phosphoprotein 1
chr7_-_27171673	0.968	NM_152739	HOXA9	homeobox A9
chr15_-_38188333	0.962	NM_001003940	BMF	Bcl2 modifying factor
chr7_-_27171648	0.956		HOXA9	homeobox A9
chr1_-_151910098	0.956	NM_004515	ILF2	interleukin enhancer binding factor 2, 45kDa
chr1_-_2451543	0.954	NM_001010926	HES5	hairy and enhancer of split 5 (Drosophila)
chr9_+_126460511	0.944
chr14_-_37795290	0.936	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr11_-_69228286	0.933	NM_005117	FGF19	fibroblast growth factor 19
chr11_+_63710162	0.896	NM_006819	STIP1	stress-induced-phosphoprotein 1
chr14_-_37795001	0.893		CLEC14A	C-type lectin domain family 14, member A
chr9_+_4782833	0.889	NM_005772	RCL1	RNA terminal phosphate cyclase-like 1
chr2_+_232281470	0.885	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr8_-_93184629	0.873	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_140772691	0.867	NM_018913 NM_032090	PCDHGA10	protocadherin gamma subfamily A, 10
chr1_-_23568854	0.867	NM_001077195	ZNF436	zinc finger protein 436
chr11_+_66764060	0.848		LOC100131150	hypothetical protein LOC100131150
chr11_+_66764064	0.831		KDM2A	lysine (K)-specific demethylase 2A
chr6_+_30796064	0.812		TUBB	tubulin, beta
chr22_+_38213174	0.802	NM_001098270	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr5_-_39460787	0.791		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_+_140537554	0.787	NM_019120	PCDHB8	protocadherin beta 8
chr1_+_22107137	0.775		RPL21	ribosomal protein L21
chr21_-_27261276	0.763	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr1_-_32574185	0.761	NM_023009	MARCKSL1	MARCKS-like 1
chr16_-_65774904	0.756		KIAA0895L	KIAA0895-like
chr5_+_140709907	0.740	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr12_-_94135154	0.736	NM_018351	FGD6	FYVE, RhoGEF and PH domain containing 6
chr19_+_60543032	0.734	NM_032701	SUV420H2	suppressor of variegation 4-20 homolog 2 (Drosophila)
chr16_-_1772305	0.727		SPSB3	splA/ryanodine receptor domain and SOCS box containing 3
chr5_+_40877053	0.725	NM_032587	CARD6	caspase recruitment domain family, member 6
chr8_-_6407882	0.717	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr5_+_50714996	0.713		ISL1	ISL LIM homeobox 1
chr12_-_23995220	0.705		SOX5	SRY (sex determining region Y)-box 5
chr1_-_151910052	0.699		ILF2	interleukin enhancer binding factor 2, 45kDa
chr17_+_56032385	0.695		PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr5_+_74668776	0.692		HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr10_-_13789628	0.692		FRMD4A	FERM domain containing 4A
chr1_-_151910057	0.689		ILF2	interleukin enhancer binding factor 2, 45kDa
chr5_-_50714836	0.687		LOC642366	hypothetical LOC642366
chr3_-_189354510	0.686		LOC339929	hypothetical LOC339929
chr5_-_39460687	0.684		DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr9_-_35101534	0.683		KIAA1539	KIAA1539
chr17_+_1566566	0.682	NM_001163673 NM_152348	WDR81	WD repeat domain 81
chr12_-_23995109	0.675		SOX5	SRY (sex determining region Y)-box 5
chr14_+_22375753	0.669		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr5_+_140194152	0.666	NM_018910 NM_031852	PCDHA7	protocadherin alpha 7
chr1_+_226404037	0.666	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr2_+_101680594	0.665	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_95165037	0.659		CNN3	calponin 3, acidic
chr5_-_159478967	0.657	NM_001130864 NM_052927	PWWP2A	PWWP domain containing 2A
chr10_+_70418482	0.654	NM_015634	KIAA1279	KIAA1279
chr17_+_43373887	0.654	NM_018129	PNPO	pyridoxamine 5'-phosphate oxidase
chr16_+_1772929	0.641	NM_012225	NUBP2	nucleotide binding protein 2 (MinD homolog, E. coli)
chr6_+_116939500	0.636	NM_153711	FAM26E	family with sequence similarity 26, member E
chr15_+_81907176	0.636		SH3GL3	SH3-domain GRB2-like 3
chr2_-_151052391	0.634	NM_005168	RND3	Rho family GTPase 3
chr22_-_30018329	0.634	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr20_-_33793286	0.631		RBM39	RNA binding motif protein 39
chr6_+_43246897	0.630	NM_003131	SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr5_+_74668748	0.629	NM_000859 NM_001130996	HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr1_+_201363458	0.623	NM_000674 NM_001048230	ADORA1	adenosine A1 receptor
chr15_+_96304911	0.622	NM_183376	ARRDC4	arrestin domain containing 4
chr17_-_69869552	0.621	NM_001080466	BTBD17	BTB (POZ) domain containing 17
chr12_+_94135645	0.617	NM_017599	VEZT	vezatin, adherens junctions transmembrane protein
chr17_+_51585834	0.617	NM_153228	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1
chr6_-_128883125	0.614	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr12_-_89922875	0.614		EPYC	epiphycan
chr1_-_151910080	0.612		ILF2	interleukin enhancer binding factor 2, 45kDa
chr6_-_75972473	0.609		COL12A1	collagen, type XII, alpha 1
chr5_+_74668799	0.609		HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr2_-_2313894	0.607	NM_015025	MYT1L	myelin transcription factor 1-like
chr1_-_151848039	0.606		S100A16	S100 calcium binding protein A16
chr5_-_125958503	0.604	NM_001182	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr18_+_3439972	0.600	NM_173209 NM_173208 NM_003244	TGIF1	TGFB-induced factor homeobox 1
chr17_-_76985538	0.589
chr5_+_74668822	0.575		HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase
chr12_-_89922888	0.571	NM_004950	EPYC	epiphycan
chr1_-_151910041	0.570		ILF2	interleukin enhancer binding factor 2, 45kDa
chr10_-_123346148	0.565	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr6_+_43247168	0.563		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr12_+_2870255	0.562	NM_001160408 NM_003324	TULP3	tubby like protein 3
chr20_-_38751289	0.555	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr15_+_96304942	0.555		ARRDC4	arrestin domain containing 4
chr16_-_30841938	0.553		NCRNA00095	non-protein coding RNA 95
chr5_+_15553768	0.550		FBXL7	F-box and leucine-rich repeat protein 7
chr14_+_22375747	0.549		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr11_+_101488380	0.548	NM_001195045	YAP1	Yes-associated protein 1
chrX_+_48265107	0.547	NM_006579	EBP	emopamil binding protein (sterol isomerase)
chr10_+_71482362	0.546	NM_018649	H2AFY2	H2A histone family, member Y2
chr1_-_23567084	0.540	NM_030634	ZNF436	zinc finger protein 436
chr6_-_30762957	0.540		KIAA1949	KIAA1949
chr11_-_27450808	0.537	NM_018490	LGR4	leucine-rich repeat containing G protein-coupled receptor 4
chr10_+_104253706	0.536	NM_001178133 NM_016169	SUFU	suppressor of fused homolog (Drosophila)
chr20_-_49818306	0.535	NM_006045	ATP9A	ATPase, class II, type 9A
chr6_+_114285209	0.532	NM_002356	MARCKS	myristoylated alanine-rich protein kinase C substrate
chr7_+_16759845	0.529	NM_014399	TSPAN13	tetraspanin 13
chr6_-_75972286	0.527	NM_004370 NM_080645	COL12A1	collagen, type XII, alpha 1
chr11_-_20138445	0.526	NM_001029865	DBX1	developing brain homeobox 1
chr3_+_195336625	0.524	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr5_-_16989371	0.522	NM_012334	MYO10	myosin X
chr7_-_13997389	0.515	NM_001163149	ETV1	ets variant 1
chr6_-_30763057	0.514	NM_001134870	KIAA1949	KIAA1949
chr9_-_35101592	0.514		KIAA1539	KIAA1539
chr7_-_27206249	0.511	NM_000522	HOXA13	homeobox A13
chr9_+_102275310	0.508	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr18_+_3437607	0.508	NM_173207	TGIF1	TGFB-induced factor homeobox 1
chr7_-_28964186	0.507
chr6_+_17390273	0.503	NM_001143941	RBM24	RNA binding motif protein 24
chr20_-_49818268	0.501		ATP9A	ATPase, class II, type 9A
chr9_+_4782876	0.501		RCL1	RNA terminal phosphate cyclase-like 1
chr2_+_62787534	0.499	NM_001142614	EHBP1	EH domain binding protein 1
chr15_+_76517623	0.498		IREB2	iron-responsive element binding protein 2
chr6_-_42218692	0.494	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr22_-_27526452	0.493		XBP1	X-box binding protein 1
chr2_-_175337386	0.491	NM_000079 NM_001039523	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr12_-_89976261	0.490	NM_007035	KERA	keratocan
chr5_+_15553736	0.488		FBXL7	F-box and leucine-rich repeat protein 7
chr7_+_20336849	0.486		ITGB8	integrin, beta 8
chr1_-_226679648	0.484	NM_003493	HIST3H3	histone cluster 3, H3
chr4_+_41309482	0.477		LIMCH1	LIM and calponin homology domains 1
chr4_+_74491272	0.477		ALB	albumin
chr14_+_85066265	0.476		FLRT2	fibronectin leucine rich transmembrane protein 2
chr10_+_104253716	0.475		SUFU	suppressor of fused homolog (Drosophila)
chr7_-_13997574	0.473	NM_001163148	ETV1	ets variant 1
chr11_-_128567302	0.473	NM_001142685	ARHGAP32	Rho GTPase activating protein 32
chr20_-_33793591	0.473		RBM39	RNA binding motif protein 39
chr12_-_24606616	0.471	NM_152989	SOX5	SRY (sex determining region Y)-box 5
chr1_+_15957832	0.469	NM_017556	FBLIM1	filamin binding LIM protein 1
chr3_+_9748769	0.467		BRPF1	bromodomain and PHD finger containing, 1
chr15_+_81906983	0.466	NM_003027	SH3GL3	SH3-domain GRB2-like 3
chr12_+_47498778	0.466	NM_000725	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr6_-_64087806	0.465	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr7_+_16652282	0.465	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr2_-_217268492	0.462	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr17_+_18069593	0.460	NM_004140	LLGL1	lethal giant larvae homolog 1 (Drosophila)
chr11_+_111313067	0.460	NM_001037954	DIXDC1	DIX domain containing 1
chr16_+_81218142	0.453		CDH13	cadherin 13, H-cadherin (heart)
chr20_-_33793593	0.453	NM_004902 NM_184234	RBM39	RNA binding motif protein 39
chr2_+_223244606	0.453	NM_058165	MOGAT1	monoacylglycerol O-acyltransferase 1
chr2_-_119322228	0.448	NM_001426	EN1	engrailed homeobox 1
chr11_-_16380967	0.448	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr12_-_11230809	0.445	NM_181429	TAS2R42	taste receptor, type 2, member 42
chr1_-_68470585	0.438	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr20_-_33793507	0.437		RBM39	RNA binding motif protein 39
chr17_+_43374021	0.437		PNPO	pyridoxamine 5'-phosphate oxidase
chr18_-_13905534	0.436	NM_000529	MC2R	melanocortin 2 receptor (adrenocorticotropic hormone)
chr11_-_85074848	0.435	NM_152723	CCDC89	coiled-coil domain containing 89
chr5_-_16989290	0.433		MYO10	myosin X
chr19_-_63205948	0.433		ZNF606	zinc finger protein 606
chr6_-_31617704	0.426		DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr6_-_31617748	0.425		DDX39B	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr6_+_31190505	0.424	NM_014068	PSORS1C1	psoriasis susceptibility 1 candidate 1
chr17_+_75366524	0.423	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr10_-_75080784	0.422	NM_024875	SYNPO2L	synaptopodin 2-like
chr7_-_5429702	0.422	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr8_-_23619866	0.420	NM_001136271	NKX2-6	NK2 transcription factor related, locus 6 (Drosophila)
chr15_-_62904857	0.416	NM_025049	PIF1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr14_+_38714111	0.416	NM_002687	PNN	pinin, desmosome associated protein
chr15_-_62460622	0.415	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr1_+_23568028	0.414		C1orf213	chromosome 1 open reading frame 213
chr5_+_140719773	0.414	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr7_-_11838260	0.414	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr6_+_43247179	0.413		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr6_+_30796123	0.413	NM_178014	TUBB	tubulin, beta
chr18_+_54039779	0.413		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr9_+_115303527	0.411	NM_130795	RGS3	regulator of G-protein signaling 3
chr12_+_121885246	0.408		HIP1R	huntingtin interacting protein 1 related
chr12_-_47362254	0.407	NM_017822	C12orf41	chromosome 12 open reading frame 41
chr18_+_18003401	0.406	NM_005257	GATA6	GATA binding protein 6
chr1_-_160260210	0.404	NM_015441	OLFML2B	olfactomedin-like 2B
chr14_+_36196523	0.404	NM_006194	PAX9	paired box 9
chr8_+_121892719	0.403
chr1_-_95165089	0.402	NM_001839	CNN3	calponin 3, acidic
chr11_+_11820096	0.399		USP47	ubiquitin specific peptidase 47
chr4_-_122964428	0.398	NM_001237	CCNA2	cyclin A2
chr11_+_11820041	0.395
chr16_+_30993252	0.394		ZNF646	zinc finger protein 646
chr14_+_62740878	0.394	NM_020663	RHOJ	ras homolog gene family, member J
chr3_-_11598829	0.394	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr4_-_159312973	0.391		FAM198B	family with sequence similarity 198, member B
chr5_+_50714714	0.390	NM_002202	ISL1	ISL LIM homeobox 1
chr12_-_106011715	0.390	NM_004075	CRY1	cryptochrome 1 (photolyase-like)
chr6_-_139737477	0.389	NM_006079	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr12_+_11694172	0.387		ETV6	ets variant 6
chr16_+_21518633	0.387		METTL9	methyltransferase like 9
chr5_+_15553539	0.386		FBXL7	F-box and leucine-rich repeat protein 7
chr3_+_85090721	0.385	NM_001167674 NM_001167675	CADM2	cell adhesion molecule 2
chr1_+_159495140	0.385	NM_001102566	PCP4L1	Purkinje cell protein 4 like 1
chr4_-_87500398	0.385	NM_138980 NM_138982	MAPK10	mitogen-activated protein kinase 10
chr16_+_81218074	0.384	NM_001257	CDH13	cadherin 13, H-cadherin (heart)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	4.17e-11	GO:0032502	developmental process
1.39	6.88e-11	GO:0007275	multicellular organismal development
1.38	9.16e-08	GO:0048731	system development
1.35	1.72e-07	GO:0048856	anatomical structure development
1.54	3.80e-07	GO:0007399	nervous system development
1.23	5.14e-06	GO:0032501	multicellular organismal process
1.10	2.66e-05	GO:0009987	cellular process
1.40	3.37e-05	GO:0030154	cell differentiation
1.39	4.96e-05	GO:0048869	cellular developmental process
1.25	2.07e-03	GO:0016043	cellular component organization
1.29	2.50e-03	GO:0071842	cellular component organization at cellular level
1.84	3.76e-03	GO:0007264	small GTPase mediated signal transduction
1.15	4.48e-03	GO:0050794	regulation of cellular process
1.53	5.21e-03	GO:0048699	generation of neurons
1.55	5.59e-03	GO:0051128	regulation of cellular component organization
2.75	5.94e-03	GO:0006334	nucleosome assembly
1.23	6.47e-03	GO:0071840	cellular component organization or biogenesis
1.27	1.12e-02	GO:0071841	cellular component organization or biogenesis at cellular level
1.50	1.21e-02	GO:0022008	neurogenesis
1.12	1.29e-02	GO:0065007	biological regulation
2.58	1.34e-02	GO:0034728	nucleosome organization
1.37	1.37e-02	GO:0009653	anatomical structure morphogenesis
2.61	1.66e-02	GO:0031497	chromatin assembly
1.57	1.79e-02	GO:0030182	neuron differentiation
1.53	2.27e-02	GO:0071844	cellular component assembly at cellular level
1.13	2.57e-02	GO:0050789	regulation of biological process
1.32	2.57e-02	GO:0048513	organ development
1.20	2.72e-02	GO:0051716	cellular response to stimulus
5.42	2.75e-02	GO:0048008	platelet-derived growth factor receptor signaling pathway
2.49	2.82e-02	GO:0065004	protein-DNA complex assembly

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.19	4.45e-05	GO:0005634	nucleus
3.47	9.61e-05	GO:0000786	nucleosome
1.09	3.91e-04	GO:0044424	intracellular part
1.08	1.27e-03	GO:0005622	intracellular
2.12	4.25e-03	GO:0031252	cell leading edge
2.56	2.07e-02	GO:0030027	lamellipodium
2.43	2.26e-02	GO:0032993	protein-DNA complex
1.53	2.34e-02	GO:0030054	cell junction
1.28	3.10e-02	GO:0031981	nuclear lumen
1.85	3.47e-02	GO:0000785	chromatin
1.09	4.08e-02	GO:0043227	membrane-bounded organelle
1.09	4.18e-02	GO:0043231	intracellular membrane-bounded organelle
1.08	4.21e-02	GO:0043226	organelle
1.08	4.62e-02	GO:0043229	intracellular organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.57	2.15e-05	GO:0001071	nucleic acid binding transcription factor activity
1.57	2.15e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
1.31	3.50e-04	GO:0003677	DNA binding
1.08	1.49e-03	GO:0005488	binding
1.13	3.12e-03	GO:0005515	protein binding